What Medications Are Prescribed to Treat Alcohol Withdrawal Syndrome (AWS) ?
Alcohol withdrawal syndrome medication is prescribed to manage withdrawal symptoms, cleanse your body of toxins, and avoid complications. The medication administered will depend on the gravity of your alcohol addiction. Here are some of the leading medications that are typically used to help you get through your alcohol detox program:
Benzodiazepines (Diazepam, Lorazepam, Chlordiazepoxide and Oxazepam)
This is the most commonly utilized medication for Alcohol Withdrawal Syndrome (AWS). They will help prevent seizures and delirium tremens (DTs), promote sedation, and reduce agitation and anxiety. These are best for patients who are dealing with severe alcohol addiction.
Anticonvulsants (Carbamazepine, Gabapentin and Valproic Acid)
Anticonvulsants, or antiepileptic drugs, can be used to deal with withdrawal symptoms for mild to moderate alcohol addiction. Benefits of these medications include a reduction in withdrawal symptoms such as agitation, seizures, and tremors, reduced alcohol cravings, and assistance in mood stabilization.
Side effects to watch out for include dizziness, sedation, weight gain, fatigue, drowsiness, nausea, blood disorders, hyponatremia, hair thinning, gastrointestinal issues, pancreatitis, and teratogenic effects.
Adrenergic Medications (Clonidine and Propranolol)
Clonidine is classified as an Alpha-2 adrenergic agonist, and it will provide relief from some autonomic symptoms of alcohol withdrawal, including sweating, high blood pressure, and elevated heart rate. Propranolol is a non-selective beta-blocker that helps manage tremors, anxiety, and tachycardia that come with alcohol withdrawal.
Antipsychotic Medications (Haloperidol and Olanzapine)
These medications assist patients in managing autonomic symptoms associated with alcohol addiction, including high blood pressure, severe agitation, hallucinations, tremors, and increased heart rate. Haloperidol is a first-generation antipsychotic that blocks dopamine D2 receptors. Olanzapine is a second-generation antipsychotic, and it blocks dopamine D2 and serotonin 5-HT2A.
Vitamins (Thiamine, Magnesium and Multivitamins)
When you’re managing alcohol withdrawal symptoms, vitamins play a huge role and address deficiencies. Lacking thiamine (vitamin B1) can cause neurological problems. Magnesium is also very common for patients who have alcohol use disorder (AUD). Multivitamins are important because alcohol addiction typically causes a shortage of those vitamins in your body.